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Genomic Analysis of Lactobacillus fermentum Strains and the Key Genes Related to Their Intestinal Anti-inflammatory Article

Yan Zhao, Chengcheng Zhang, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Engineering 2022, Volume 17, Issue 10,   Pages 170-182 doi: 10.1016/j.eng.2020.09.016

Abstract:

•Some specific genes may account for the anti-inflammatory and immunoregulation of branches of the phylogenetic tree and strain type L. fermentum CECT5716 were selected and their anti-inflammatoryThe anti-inflammatory mechanisms of L. fermentum FXJCJ61 and CECT5716 were related to the inhibitionComparative genomic analysis of these strains identified candidate genes that may contribute to the anti-inflammatory

Keywords： Lactobacillus fermentum     Ulcerative colitis     Anti-inflammation     Phylogenetic analysis     Comparative    

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Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2? Review

Lin Li, Yuzheng Wu, Jiabao Wang, Huimin Yan, Jia Lu, Yu Wan, Boli Zhang, Junhua Zhang, Jian Yang, Xiaoying Wang, Min Zhang, Yue Li, Lin Miao, Han Zhang

Engineering 2022, Volume 19, Issue 12,   Pages 139-152 doi: 10.1016/j.eng.2021.08.020

Abstract:

Traditional Chinese medicine (TCM) has been successfully applied worldwide in the treatment of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the pharmacological mechanisms underlying this success remain unclear. Hence, the aim of this review is to combine pharmacological assays based on the theory of TCM in order to elucidate the potential signaling pathways, targets, active compounds, and formulas of herbs that are involved in the TCM treatment of COVID-19, which exhibits combatting viral infections, immune regulation, and amelioration of lung injury and fibrosis. Extensive reports on target screening are elucidated using virtual prediction via docking analysis or network pharmacology based on existing data. The results of these reports indicate that an intricate regulatory mechanism is involved in the pathogenesis of COVID-19. Therefore, more pharmacological research on the natural herbs used in TCM should be conducted in order to determine the association between TCM and COVID-19 and account for the observed therapeutic effects of TCM against COVID-19.

Keywords： Traditional Chinese medicine     SARS-CoV-2     COVID-19     Antivirus     Anti-inflammation     Immune regulation    

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Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 314-329 doi: 10.1007/s11684-018-0625-0

Abstract: Meanwhile, chronic low-grade inflammation is commonly observed in obese populations.

Keywords： cytokines     inflammation     adipogenesis     type 2 diabetes mellitus     metabolic disorder    

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Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth

Khurram Siddique, Shirin Mirza, Gandra Harinath

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 264-269 doi: 10.1007/s11684-013-0259-1

Abstract:

The effect of the severity of appendiceal inflammation on post-operative stay in children followingThis study was conducted to determine the association between the severity of appendiceal inflammationThe association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariableMacroscopically perforated appendix, histological inflammation and post-operative complications wereperforated appendix or post-operative complications while it remained unaffected by the histological inflammation

Keywords： appendiceal inflammation     post-operative stay     paediatrics    

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for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on peritoneal inflammation

Zhen Zhang, Na Jiang, Zhaohui Ni

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 349-358 doi: 10.1007/s11684-017-0571-2

Abstract: Inflammation and angiogenesis are key events during the pathogenesis of peritoneal fibrosis.peritoneal fibrosis and recent research progress on key fibrogenic molecular mechanisms in peritoneal inflammationFurthermore, novel strategies targeting peritoneal inflammation and angiogenesis to preserve the PM are

Keywords： peritoneal dialysis     peritoneal fibrosis     inflammation     angiogenesis    

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Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 750-766 doi: 10.1007/s11684-021-0839-4

Abstract: Exposure to particulate matter 2.5 (PM2.5) potentially triggers airway inflammation by activating nuclearSirtuin 2 (SIRT2) is a key modulator in inflammation.However, the function and specific mechanisms of SIRT2 in PM2.5-induced airway inflammation are largelyThe activation of p65 triggered airway inflammation, increment of mucus secretion by goblet cells, andMeanwhile, p65 phosphorylation and acetylation, airway inflammation, and bronchial hyperresponsiveness

Keywords： particulate matter 2.5     sirtuin 2     p65     airway inflammation     bronchial hyperresponsiveness     triptolide    

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QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 2,   Pages 306-332 doi: 10.15302/J-FASE-2023488

Abstract:

● Using visual analysis to predict the trend of natural product pest resistance.

Keywords： anti-pest activity     crop protection     insect pest     natural product     visual analysis    

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Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 638-643 doi: 10.1007/s11684-021-0831-z

Abstract: role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation

Keywords： COVID-19     endothelial dysfunction     inflammation reaction     cytokine storm    

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Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 729-746 doi: 10.1007/s11684-022-0978-2

Abstract: The effect of anti-programmed cell death 1 (anti-PD-1) immunotherapy is limited in patients with hepatocellularThe response to anti-PD-1 treatment is associated with A. muciniphila abundance in many tumorsHere, anti-PD-1 treatment decreased A. muciniphila abundance in the colon, but increased YAP1Yap1 knockout enhanced anti-PD-1 efficacy.Our findings suggested that the combination anti-PD-1 with DHA is an effective strategy for liver tumor

Keywords： hepatocellular carcinoma     YAP1     Akkermansia muciniphila     anti-PD-1     dihydroartemisinin     bile acid    

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Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 25-34 doi: 10.1007/s11684-008-0006-1

Abstract: Over-reabsorption of filtered proteins, notably albumin, has been proved to trigger interstitial inflammationalbumin-induced production of MCP-1 and RANTES by renal tubular cells, which further initiated tubulointerstitial inflammation
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A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0722-2

Abstract: This paper proposes a novel modular cable-driven humanoid arm with anti-parallelogram mechanisms (APMs

Keywords： modular robotic arm     anti-parallelogram mechanism     Bowden cable     humanoid arm     lightweight joint design    

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Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 1866-1878 doi: 10.1007/s11705-023-2340-x

Abstract: review, research efforts over the past few years to mitigate the immune responses by enhancing the anti-biofoulinglayers on the biosensor surface, such as drug-releasing membranes, hydrogels, hydrophilic membranes, anti-biofoulinginformation, which is likely to aid in the research and development of novel CGM systems with profound anti-biofouling

Keywords： implantable glucose biosensor     anti-biofouling     continuous glucose monitoring     immune responses    

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Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 242-254 doi: 10.1007/s11684-013-0256-4

Abstract:

Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a majorThis review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss

Keywords： hepatocellular carcinoma     hepatitis     cytokine     stem cell     miRNA    

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Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 966-975 doi: 10.1007/s11705-022-2244-1

Abstract: Compared with green and blue fluorescent materials, red SPN-CDs have desirable anti-interference properties

Keywords： alkali lignin     red light carbon dots     hypochlorite     encryption and anti-counterfeiting    

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Discovery and repurposing of artemisinin

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 1-9 doi: 10.1007/s11684-021-0898-6

Abstract: We will then discuss how artemisinin and its derivatives could be repurposed to treat cancer, inflammation

Keywords： artemisinin     drug repurposing     cancer     inflammation     COVID-19     traditional Chinese medicine    

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Title Author Date Type Operation

Genomic Analysis of Lactobacillus fermentum Strains and the Key Genes Related to Their Intestinal Anti-inflammatory

Yan Zhao, Chengcheng Zhang, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Journal Article

Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2?

Lin Li, Yuzheng Wu, Jiabao Wang, Huimin Yan, Jia Lu, Yu Wan, Boli Zhang, Junhua Zhang, Jian Yang, Xiaoying Wang, Min Zhang, Yue Li, Lin Miao, Han Zhang

Journal Article

Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Journal Article

Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth

Khurram Siddique, Shirin Mirza, Gandra Harinath

Journal Article

for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on peritoneal inflammation

Zhen Zhang, Na Jiang, Zhaohui Ni

Journal Article

Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating

Journal Article

QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Journal Article

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Journal Article

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Journal Article

Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Journal Article

A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Journal Article

Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Journal Article

Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Journal Article

Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Journal Article

Discovery and repurposing of artemisinin

Journal Article